Although single cell RNA sequencing studies have begun providing compendia of cell expression profiles, it has proven more difficult
to systematically identify and localize all molecular cell types in individual organs to create a full molecular cell atlas. From
droplet- and plate-based single cell RNA sequencing applied to ~75,000 human lung and blood cells, combined with a multi-pronged cell annotation
approach that includes extensive tissue localization, we have defined the gene expression profiles and anatomical locations of 58 cell populations
in the human lung, including 41 of 45 previously known cell types or subtypes and 14 new ones. Learn more in our
manuscript and our GitHub repository.
cellxgene
Explore the data in your browser on cellxgene.cziscience.com hosted by the Chan Zuckerberg Initiative:
Data availability
Download count/UMI tables, metadata, and Seurat and scanpy objects for your own bioinformatic piplines from Synapse. Raw sequencing reads are available on the European Genome-phenome Archive. Please complete our Data Access Agreement and return to our Data Access Committee to request access.